Autoimmune theory of dental caries

By Dental Tribune International April 23, 2019 TORONTO, Canada: The question as to why the human immune system partly works against the body, for example in autoimmune diseases, is still not sufficiently researched. Usually, it is the conjunctive tissue that is affected Chemical (acid) theory. Parmly (1819) proposed that an unidentified chymical agent was responsible for caries. According to this theory, teeth are destroyed by the acids formed in the oral cavity by the putrefaction of protein which produced ammonia and was subsequently oxidized to nitric acid This causes an increased risk of dental caries, fungal infections, and chronic oral discomfort. As such, dentists play a key role in the diagnosis and management of this disease [ 25 ]. SjS pathogenesis occurs through a combination of genetic, environmental, and hormonal factors, leading to the development of inflammation and autoimmune. A Mutans Streptococci initiate the dental caries process and other bacteria such as lactobacilli become involved at a later state when the plaque pH is lower. P.gingivalis is a bacterium that causes gingival inflammation Common Autoimmune Diseases. More than 100 autoimmune diseases affect 5% of the population. I will cover the more common ones and their oral health symptoms and risk factors that pertain to dentistry. 1 The commonality of autoimmune diseases tends to be older age, women, genetics, and Caucasians. The common oral health effects tend to be mouth sores, dry mouth, an increase in dental cavities.

Human immune system contributes to dental caries and

Autoimmune theory claims that autoantibodies and serum factor present in blood cause release of histamine from skin mast cells and basophiles. The main argument against this theory is that antibodies found in chronic urticaria (autoantibodies to IgE, FcɛRI) are not specific to the disease Dilley et al, 1980 A unique pattern of dental caries in young children. genes (autoimmune theory) 36. STEPHAN's curve It is the pH below which a tooth is subjected to DEMINERALIZATION Mean Value is 5.5 37. 38. 39. CURRENT CONCEPT IN THE PATHOGENESIS OF DENTAL CARIES MCQs: A patient with carinoma cheek has tumor of 2.5 cms located close to and involving the lower alveolus.A single mobile homolateral node measuring node measuring 6 cm is palpable. Based on these clinical findings TNM stage of the tumor is_____ D. Autoimmune theory # The correct order of microscopic zones of dentinal caries starting from the DEJ is : A. Zone of sclerosis, decalcification zone, bacterial invasion B. Bacterial invasion, decalcification zone, zone of sclerosi


Periodontal diseases are characterized by localized infections and inflammatory conditions that directly affect teeth supporting structures which are the major cause of tooth loss. Several studies have demonstrated the involvement of autoimmune responses in periodontal disease. Evidences of involvement of immunopathology have been reported in periodontal disease. Bacteria in the dental plaque. The connection of MS to dentistry has been known for a long time but is rarely discussed in the literature. Craelius (1978) reported the global demographic overlap of deaths due to MS with the DMF (decayed, missing, filled) distribution. He said, A review of the literature shows that the risk for dental caries is lower among blacks compared with whites; and males compared with females Oral manifestations  RA is associated with xerostomia (dry mouth), which increases the risk of dental caries.  As with other autoimmune diseases, compromise of the immune system (be it from the disease or the treatment) elevates the risk of periodontal disease Primary Sjögren's syndrome (pSS) is associated with dental caries. Pilocarpine, a salivary stimulant, can improve the amount and flow rate of saliva in patients with pSS. This study aimed to assess whether the risk of dental caries decreases with the use of pilocarpine in patients with pSS

Dental professionals can engage in refined assessment for autoimmune diseases by taking a careful health history and using probing questions for manifestations of problems suggesting an autoimmune component. Table 2 presents a risk assessment tool that can aid clinical decision-making. 12 Performing a thorough medical, oral and pharmacologic. Caries and oral mucosal and periodontal diseases are the major cause of oral health problems. They are prevalent in all ages and demographic and socioeconomic groups. Irrespective of geographic location in the world, both males and females are affected from the condition. Dental caries' etiology has four main factors: bacteria, time, susceptible tooth surface, and fermentable carbohydrates In 1898, Miller presented the chemistry-parasitic theory of caries development, universally recognized and confirmed by many scientists. The essence of the theory is that microorganisms of the oral cavity, which cause caries of teeth, in the presence of special low-molecular carbohydrates, produce organic acids

Caries Disease . Dental caries, also known as tooth decay or a cavity, is an infection, bacterial in origin, that causes demineralization and destruction of the hard tissues of the teeth (enamel, dentin, and cementum). An infectious microbiological disease of the teeth that results in localized dissolution and destruction of the calcified. Dental caries is one of the most common diseases of mankind (Marcenes et al., 2013). Despite recent reductions in the rate of decay in Western societies, the prevalence of caries in developed countries remains at greater than 95% of the population. Caries is still increasing in developing countries with the increased consumption of refined sugars Currently, the traditional theory of dental caries considers only the oral environment and does not recognize any significant role for the brain. The healthy tooth, however, has a centrifugal fluid flow to nourish and cleanse it. This is moderated by the hypothalamus/parotid axis which signals the endocrine portion of the parotid glands

Autoimmunity and the Oral Cavity SpringerLin

Dental CARIES is an irreversible microbial disease of the calcified tissues of the teeth. It is characterized by demineralization of the inorganic portion and destruction of the organic substances of the tooth Dental caries /certified fixed orthodontic courses by Indian dental academy Autoimmune Theory Few odontoblast cells at specific sites within pulp of specific teeth are damaged by autoimmune mechanism Due to this the defense capacity & integrity of of enamel and dentin in those specific areas are compromised and act as potential sites for. AUTOIMMUNE THEORY : Jackson and Burch (1972) proposed that clones or regions of odontoblasts in specific sites within the pulp of specific teeth are damaged by an autoimmune process so that defence capacity of overlying dentin is compromised. These areas determine the sites of caries susceptibility 1. Career Institute of Dental Sciences and Hospital, Lucknow, India, Purvanchal Institute of Dental Sciences, Gorakhpur, Uttar Pradesh, India, Buddha Institute of Dental Sciences and Hospital, Patna, Bihar, Indi Parasitic theory: Theory proposed by Erdl First to relate microorganisms as causative agent is Erdl in 1843 Fincus, in 1847, a German physician attributed dental caries to‗DENTICOLAE' Generic name proposed to decay related organisms Theory stated that living micro organisms caused the disintegration in bothenamel and denti

For optimal dental appointment outcomes, it's important to go the extra mile for patients living with a chronic illness. Karen Davis, BSDH, RDH, explains the basics of the spoon theory and how it's relevant to your practice Essentials of Dental Caries The Disease and Its Management, 3rd Ed (Kidd, Essentials of Dental Caries Autoimmune diseases are the third most common category of disease in the United States after cancer and heart disease; they affect approximately 5%-8% of the population or 14-22 million persons. •Often the disease starts during a woman's childbearing years (ages 15 to 44). Some autoimmune diseases are more common in certain ethnic groups autoimmune diseases may reduce morbidity associated with such diseases. Summary Autoimmune diseases impact the oral cavity both directly and indirectly and are increasing in prevalence. As such, there is a growing need for the oral health practitioners to be aware of how autoimmune disease impacts the oral cavity. Furthe Context: Systemic autoimmune and inflammatory diseases often manifest oral lesions in their earliest stages, and early diagnosis, which may be spurred by a dental examination, is key for improved outcomes. After systemic diagnosis, oral lesions benefit from specialized care by dentists in collaboration with the medical team. This review aims to educate dental clinicians about the most relevant.

port33, caries, despite of all efforts and measures undertaken to control the disease, is still identifi-able as a continuing global health care problem. The consequence of caries are not limited to the destruction of tooth substance that results in needs for dental restoratives, crown and bridge-works as well as implants in case of tooth loss Microbiota of dental caries Dental caries happens mainly when the production of organic acid results in dental hard tissue decalcification. Thus, dental caries bacteria should be acid-tolerant in carrying out the dental caries process in an acidic environment. [17] Acidogenic bacteria, e.g. S. mutans, are able to function at pH 6 and can carry ou Caries Disease Dental caries, also known as tooth decay or a cavity, is an infection, bacterial in origin, that causes demineralization and destruction of the hard tissues of the teeth (enamel, dentin, and cementum). An infectious microbiological disease of the teeth that results in localized dissolution and destruction of the calcified tissues Haptonstall's UCLA lab, lead by Molly Fox, PhD, believes in the transient bacteremia theory. This theory expands on the idea that when you floss, have a dental procedure, or disrupt the mucosal barrier in the mouth (think about getting a cut on your skin) oral bacteria can enter the bloodstream and subsequently get into the brain

Dental caries - MCQs - Focus Dentistr

  1. The World Health Organization estimates that nearly all adults have dental caries at some point in time. 1 Resin composite is the most used restorative material in dentistry; 2 most resin composite restorations are placed due to secondary caries or recurrent caries that cause restoration failure at a cost of $30 billion a year in North America. 3 The restoration may fail over time because its.
  2. Around 85% of Lupus Warriors experience tooth decay during the battle with lupus. As if the pain and fatigue wasn't enough! Many people with lupus experience dental caries, better known as cavities, in their life. Lupus Warriors may find it valuable to go to the dentist more frequently, going up to 4 times a year (or every 3 months)
  3. The dental team may be the first health-care members to notice the oral lesions that occur in pemphigus vulgaris, and they are a crucial link, assisting the patient in obtaining the necessary medical care that is needed. Early treatment is crucial in controlling pemphigus vulgaris. Sirois, et al. (2000) reported that more than 50 percent of.
  4. Dental caries began to decline in the 1950s among children who grew up in fluoridated cities, and by the late 1970s, decline in decay was evident for many Americans. The application of science to improve diagnostic, treatment, and prevention strategies has saved billions of dollars per year in the nation's annual health bill
  5. Dental caries is one of mankind's ancient and longest disease associated with the oral profession. Everyday around 2.3 billion people are affected by dental caries. But since the late 20th century with new advancement in technologies there is slow but gradual progress in the development of the vaccine .1972, a caries vaccine was said to be in.
  6. the tongue, increased incidence of dental caries, super-ficial mouth ulcers and cheilitis (Figure 1a) (Ravald and List, 1998). Likewise, ocular manifestations may include erosions of the cornea, conjunctivitis and in severe cases corneal ulceration (Kassan and Moutsopoulos, 2004). The most important sequel of SS, although, is th
  7. While the cause may be a serious underlying disorder, such as caries or a cracked tooth, the problem is more often due to a relatively trivial condition known as dental or dentinal hypersensitivity. 1 Dentinal hypersensitivity is not a direct cause of tooth loss, but patients benefit greatly from advice on prevention and treatment. 2 The.

Autoimmune Diseases: Making Sense of Dental Patients

Widely accepted theory of dental caries_____? 0. A. Proteolytic theory B. Proteolytic chelation theory C. Acidogenic theory D. Autoimmune theory. The number of dentinal zones in dentinal caries is_____? 0. A. One B. Two C. Four D. Five. In a patient with reduced salivary flow the carious incidence is_____? 0. A. More than the patient with. Dental caries is the most prevalent chronic disease affecting the human race. In many ways it can be considered a disease of modern times as the occurrence of caries seems to be much higher in the last few generations. It is said that once it occurs the scars persists throughout life even though the lesion is treated

The role of focal infections in the pathogenesis of

Some believe that dental caries is the result of a vitamin-deficient diet. Others think it is due to a derangement of the endocrine glands, or the organs of internal secretion. Another says it is due to the composition of the salivary fluid. Again, that it is due to a diet of denatured, or civilized, food. The above causes, however, are really. Dental Caries - Principles and Management (2016).pd Essentials of Dental Caries The Disease and Its Management, 3rd Ed (Kidd, Essentials of Dental Caries

Widely accepted theory of dental caries

  1. Autoimmune Diseases and the potential role of Chinese Herbal Medicine tongue ulcers, and severe dental caries (which occur because of the lack of saliva). The other autoimmune diseases fall into several groupings, among the most common are these: some deficiencies would be observed. Otherwise, the TCM theory would have to be.
  2. Acidogenic Theory or the Chemicoparasitic theory explained by D Miller about the Etiology of Dental caries is the most widely accepted and most useful, which helps you understand the actual cause of Caries. This theory is a blend of 2 theories explained in the earlier parts of 1800′s - Chemicoparasitic Theory: Chemical Theory + Parasitic Theory Theory: Caries is cause
  3. Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED), also known as autoimmune polyglandular syndrome type 1 (APS-1), is a rare genetic disorder caused most often by biallelic mutations in the AIRE gene. Classic clinical findings of the disease are chronic mucocutaneous candidiasis and autoimmunity that primarily targets endocrine tissues, such as hypoparathyroidism and.

Plaque hypotheses are theories to explain the role of plaque bacteria in dental caries and in periodontitis.They rely heavily on the postulates of Koch (formulated in 1884) and on the work of Louis Pasteur (1822-1895). Changing perceptions have altered treatment models.. The hypotheses have sought to establish both in caries and in periodontitis a relation between pathogen virulence. Sjogren's syndrome is a chronic disorder first described by Swedish eye doctor Henrick Sjogren which causes a lack of sufficient moisture production in specific glands in a person's body. Sjogren's syndrome is an autoimmune disease that occurs when a person's immune system attacks and destroys their moisture-producing glands

Dentosphere : World of Dentistry: MCQs on Dental Carie

Dental caries is a multifactorial irreversible microbial disease of the calcified tissues of the teeth, which is characterized by demineralization of the inorganic portion and destruction of the organic substance of the tooth, which often leads to cavitation. Dental caries is one of mankind's ancient and longest disease associated with the. 27 Autoimmume theory: The autoimmune theory of dental caries suggests that few odontoblast cells at some specific site within the pulp of few specific teeth are damaged by the autoimmune mechanisms. For this reason the defense capacity and integrity of the overlying enamel or dentin in those specific areas are compromised, and they can be the. Back and better than ever, Darby and Walsh's Dental Hygiene: Theory and Practice, 5th Edition offers everything you need to succeed in your coursework, at certification, and in clinical practice. No other dental hygiene text incorporates the clinical skills, theory, and evidence-based practice in such an approachable way. All discussions — from foundational concepts to diagnosis to pain. Tooth decay, also known as dental caries or cavities, is the breakdown of teeth due to acids made by bacteria. The cavities may be a number of different colors from yellow to black. Symptoms may include pain and difficulty with eating. Complications may include inflammation of the tissue around the tooth, tooth loss, and infection or abscess formation.. Vital Theory: The vital theory regarded dental caries as originating within the tooth it self, analogous to bone gangrene. This theory proposed at the end of the 18 th century, remained dominent.

Role of Autoimmune Responses in Periodontal Diseas

3.1. The support of a systemic theory of dental caries and K2 as a critical component. The old theory of dental health, called the 'acid theory,' has been linked to the oral environment as an isolated and unique process, involving the bacteria-acid axis, as it is the only cause-effect relationship Early theories of caries etiology 1. Worms According to an ancient Sumerian text, tooth ache was caused by a worm that drank the blood of the teeth and fed on the roots of the jaws. Guy de Cahuliac (1300-1368) the greatest surgeon of the middle ages believed that worms caused dental decay. As a cure he advocated fumigation with seeds of leek, onion and hyoscyamus The study, published in the open-access journal BMC Public Health, an alysed the effect of sugars on dental caries, also known as tooth decay. They show that sugars are the only cause of tooth decay in children and adults No other dental hygiene text incorporates the clinical skills, theory, and evidence-based practice in such an approachable way. All discussions — from foundational concepts to diagnosis to pain management — are presented within the context of a unique patient-centered model that takes the entire person into consideration

Dental Hygiene Associate of Science Degree. Offered at the Following Campus Locations. Savannah Campus; Program Overview. The program in Dental Hygiene is accredited by the Commission on Dental Accreditation [and has been granted the accreditation status of approval without reporting requirements] The Commission is a specialized accrediting body recognized by the United States Department. Description. Back and better than ever, Darby and Walsh's Dental Hygiene: Theory and Practice, 5th Edition offers everything you need to succeed in your coursework, at certification, and in clinical practice. No other dental hygiene text incorporates the clinical skills, theory, and evidence-based practice in such an approachable way Get the hands-on practice and reinforcement you need to master the concepts and skills covered in Darby & Walsh's Dental Hygiene: Theory and Practice, 5th Edition.The chapters in this workbook directly correlate to textbook chapters and provide ample review questions and exercises, competency skills evaluation sheets, case studies, and information for your clinical externship and. Sucrose (Arch criminal of caries) 1. The most consumed CHO 2. Low molecular weight, can diffuse rapidly into dental plaque. 3. It is readily metabolized by many bacteria involved in dental biofilm formation 4. Importance of Sucrose depends on the high energy of its glucose-fructos

Dental Caries. Cavities of the teeth, known clinically as dental caries, are microbial lesions that cause damage to the teeth. Over time, the lesion can grow through the outer enamel layer to infect the underlying dentin or even the innermost pulp Acidogenic Theory or the Chemicoparasitic theory explained by D Miller about the Etiology of Dental caries is the most widely accepted and most useful, which helps you understand the actual cause of Caries. This theory is a blend of 2 theories explained in the earlier parts of 1800's - Chemicoparasitic Theory: Chemical Theory + Parasitic [&helli 1. Southward K. The systemic theory of dental caries. Gen Dent. 2011;59(5):367-73. 2. Touger-decker R, Van loveren C. Sugars and dental caries. Am J Clin Nutr. 2003;78(4):881S-892S. 3. Utturkar SM, Klingeman DM, Land ML, et al. Evaluation and validation of de novo and hybrid assembly techniques to derive high quality genome sequences a large proportion of dental decay, but other low-pH plaque species may blaze the trail for these bad species of Streptococcus, Banas explained. Although this has been the theory, there is sparse evidence for the roles of highly acidogenic (low pH) streptococcal species besides S. mutans and S. sobrinus. We will be able to see how the low p

on age-specific occurrence applied to some typical autoimmune disorders, notably SLE,17 and some less well-validated chronic dis-orders including Dupuytren's fibrotic contracture of the fingers,18 psoriasis, dental caries and others. Burch emphasized the stochastic nature of the occurrence of these diseases, and theorized that the age are direct and indirect sequelae of caries disease [3, 4]. The high prevalence of dental caries in certain groups of the society in combination with limited effectiveness of the traditional education-based efforts to improve oral hygiene behaviors for caries prevention [5, 6] highlights the necessity to develop new strategies in caries control

Does Dentistry Hold The Missing Link to Multiple Sclerosis

BACKGROUND: APECED (Autoimmune Polyendocrinopathy Candidiasis Ectodermal Dystrophy) is a rare autosomal recessive disease characterised primarily by sequential immune-mediated destruction of endocrine tissues, chronic oral or mucocutaneous candidiasis and ectodermal disorders, including hypoplasia of dental enamel Jan. 22, 2020 — Cavities, or dental caries, are the most widespread non-communicable disease globally, according to the World Health Organization. Having a cavity drilled and filled at the. In dentistry, the most important oral infection is dental caries and is found almost in every individual. To describe the process of dental caries, various theories have been postulated. These theories have stated about the mechanism of dental caries formation. These theories are Worm theory,[2] Humora Contrary to mainstream dental theory, it seems that not all cavities are caused by sugar. (See The Vipeholm Dental Caries Study: Recollections and Reflections 50 Years Later .) The Vipeholm results strongly suggest that sugar isn't very damaging to your teeth unless it is consumed between meals

Dental erosion, halitosis, odynophagia, dysphagia, high prevalence of caries, granulomatous and autoimmune-like changes in minor salivary glands, and reduced sali vation have also been reported (12). Table 2 provides a summary of specific and nonspecific changes associated with IBD. Orofacial granulomatosis Crohn's disease Ulcerative coliti Dental caries- Theories, etiology, factors, histopatholog Evidence in the literature suggests there may be a relationship between mercury from dental amalgams and MS. Epidemiology studies have linked dental caries with MS. 8 In Australia the rates of death due to MS are linearly related to the number of decayed, missing, and filled teeth: (r=0.9, P=0.002). In the United States a direct correlation. The association of HLA class II alleles, such as HLA-B44, DQB1*0302, HLA-DRB1*01, HLA DRB1*04, HLA-DRB*15, confirms the autoimmune theory of the pathogenesis of chronic urticaria and may be the genetic factor in this process [54-56]. Serum of the patients with the positive result of the autologous serum skin test had significantly increased.

Tooth decay appears to be a significant oral health concern for older adults [7,8]. Currently, dental caries is by far the most common medical disorder impacting 2 - 4/2.4 billion individuals worldwide [9]. Three age trends are correlated with dental caries: 6, 25 and 70 years of age [9] The reduction in saliva increases the likelihood of dental caries, enamel erosion, and periodontal disease. Although it is clear that use of the drug decreases saliva, the mechanism by which it does so is unclear. One theory is that the drug causes vasoconstriction (narrowing of the blood vessels) in salivary glands, decreasing salivary flow Prevention of caries is an important principle of maintaining healthy teeth. Since the main condition for the appearance of streptococcus accumulations is dental plaque, prevention of caries should begin with regular oral hygiene. If you do not create comfortable conditions for the life of streptococci, the risk of their occurrence is minimized Clinical applications and performance of intelligent systems in dental and maxillofacial radiology: A review Ravleen Nagi, 1 Konidena Aravinda, 1 N Rakesh, 2 Rajesh Gupta, 1 Ajay Pal, 1 and Amrit Kaur Mann 1: 1 Department of Oral Medicine and Radiology, Swami Devi Dyal Hospital and Dental College, Panchkula, India.: 2 Department of Oral Medicine and Radiology, Faculty of Dental Sciences, M.S.

Dental hygiene : theory and practice / Michele Leonardi Darby Darby, Michele Leonardi Dental caries management by risk assessment / John D. B. Featherstone -- Periodontal Persons with autoimmune diseases / Margaret M. Walsh -- Renal disease and organ transplantation / Cheryl Thomas -- Respiratory diseases To be successful in assessing and managing caries risk among these populations, one should consider all the patient modifying factors in a systematic way. In this article, the authors discuss how to provide a program of personalized and effective dental caries management for frail older adults and persons with special needs Back and better than ever, Darby and Walsh's Dental Hygiene: Theory and Practice, 5th Edition offers everything you need to succeed in your coursework, at certification, and in clinical practice. The majority of data on selenium and thyroid disease are regarding chronic autoimmune thyroiditis. of dental caries). It is also present in such products as tea, processed foods, dental.

African Journal of Microbiology Research, Vol 2:3 pp 63-66, MAR 2008. < TD Anand, C Pothiraj, RM Gopinath, et al. Effect of oil-pulling on dental caries causing bacteria> Oil Pulling Recommendations Given what we now know about oil pulling, it might be better to refer to it by its less common name, oil swishing, since there probably is no. Dental Caries - Theories - Clinical features - Classification - Histopathology - Immunology - Caries activity Tests - Factors Influencing Caries: 5 hour : 3) Diseases of the pulp and Periapical tissues : 5 hour: a) Diseases of the Dental Pulp - Pulpitis, Focal Reversible Pulpitis, Chronic Pulpitis, Pulp Polyp.. b) Diseases of the Periapical Tissue This is the effect of dental fluorosis, the first visible sign of overexposure to fluoride. In some communities, the incidence of dental fluorosis is 30 to 60 percent or more. Fluoride ingestion from mouth rinses and dentifrices in children is extremely hazardous to biological development, life span and general health

Dental Caries & Raynaud's Disease Symptom Checker: Possible causes include Sjögren Syndrome. Check the full list of possible causes and conditions now! Talk to our Chatbot to narrow down your search Dental problems are compounded when salivary flow is reduced. A dry mouth is a common complaint with celiac. Saliva has a major role in preventing dental caries. If the enamel is weak already, then major dental problems can advance quickly These medications may cause xerostomia, which may lead to increased dental caries and periodontal disease because there is no saliva to aid in the removal of bacterial plaque—which in turn leads to decay, and bone loss. Chronic pain patients may learn helplessness, which causes apathy and lack of desire to participate in dental hygiene The Theory and Application Bacterial Interference to Oral Diseases. Probiotics could also conceivably be put to use in preventing disease or thwarting autoimmune disorders. A number of these possibilities are being explored in research laboratories and hospitals around the world. Dental caries is the most common chronic disease of.

The effect of pilocarpine on dental caries in patients

Its association with other autoimmune diseases like vitiligo and Hashimoto's thyroiditis gives further credence to this theory. The inflammatory cell accumulation seen in histopathology is also a strong corraborator. Direct Pressure: See the Box below. Mobile phones and alopecia areata! (See the Box below). Caries Tooth: See the Box below Despite all these issues, progress has been made in determining the bacterial etiology of dental caries disease. In the late nineteenth century, Dr W.D. Miller put forward the chemico-parasitic theory of caries disease, in which he proposed that oral microorganisms can break down dietary carbohydrates to acids which demineralize enamel Certain clinical broken tooth, dental caries or periodontal disease. By activities initiate or heighten dentin hypersensitivity. certain autoimmune disorders or a history of radiation neural response to pain stimuli.7,16 Potassium salts are well treatment in the oral cavity all contribute to xerostomia. A second theory proposed by.